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BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.

TitleBeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.
Publication TypeJournal Article
Year of Publication2002
AuthorsGrant, JD, Dunbrack, RL, Manion, FJ, Ochs, MF
JournalBioinformatics
Volume18
Issue5
Pagination765-6
Date Published2002 May
ISSN1367-4803
KeywordsComputer Communication Networks, Computing Methodologies, Database Management Systems, Databases, Genetic, Information Storage and Retrieval, Internet, National Library of Medicine (U.S.), Sequence Analysis, United States
Abstract

UNLABELLED: BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through its web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.AVAILABILITY: Source code is available under the GNU public license at http://bioinformatics.fccc.edu/

Alternate JournalBioinformatics
PubMed ID12050075
People: 
Frank Manion
University of Michigan Comprehensive Cancer Center at North Campus Reserach Complex
1600 Huron Parkway, Bldg 100, Rm 100 
Mailing Address: 2800 Plymouth Rd, NCRC 100-1004
Ann Arbor, MI 48109-2800 
Ph. (734) 764-8848 Fax. (734) 615-0517
Please acknowledge the Cancer Center Support Grant (P30 CA046592) when publishing manuscripts or abstracts that utilized the services of the University of Michigan's Comprehensive Cancer Center's Shared Resource: Cancer Informatics.
Suggested language: "Research reported in this [publication/press release] was supported by the National Cancer Institute of the National Institutes of Health under award number P30CA046592."

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