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BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.

TitleBeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.
Publication TypeJournal Article
Year of Publication2002
AuthorsGrant, JD, Dunbrack, RL, Manion, FJ, Ochs, MF
Date Published2002 May
KeywordsComputer Communication Networks, Computing Methodologies, Database Management Systems, Databases, Genetic, Information Storage and Retrieval, Internet, National Library of Medicine (U.S.), Sequence Analysis, United States

UNLABELLED: BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through its web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.AVAILABILITY: Source code is available under the GNU public license at

Alternate JournalBioinformatics
PubMed ID12050075
Frank Manion
University of Michigan Comprehensive Cancer Center at North Campus Reserach Complex
1600 Huron Parkway, Bldg 100, Rm 100 
Mailing Address: 2800 Plymouth Rd, NCRC 100-1004
Ann Arbor, MI 48109-2800 
Ph. (734) 764-8848 Fax. (734) 615-0517
Please acknowledge the Cancer Center Support Grant (P30 CA046592) when publishing manuscripts or abstracts that utilized the services of the University of Michigan's Comprehensive Cancer Center's Shared Resource: Cancer Informatics.
Suggested language: "Research reported in this [publication/press release] was supported by the National Cancer Institute of the National Institutes of Health under award number P30CA046592."

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