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BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.

TitleBeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.
Publication TypeJournal Article
Year of Publication2002
AuthorsGrant, JD, Dunbrack, RL, Manion, FJ, Ochs, MF
JournalBioinformatics
Volume18
Issue5
Pagination765-6
Date Published2002 May
ISSN1367-4803
KeywordsComputer Communication Networks, Computing Methodologies, Database Management Systems, Databases, Genetic, Information Storage and Retrieval, Internet, National Library of Medicine (U.S.), Sequence Analysis, United States
Abstract

UNLABELLED: BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through its web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.AVAILABILITY: Source code is available under the GNU public license at http://bioinformatics.fccc.edu/

Alternate JournalBioinformatics
PubMed ID12050075
People: 
Frank Manion
University of Michigan Rogel Cancer Center at North Campus Research Complex
1600 Huron Parkway, Bldg 100, Rm 1004 
Mailing Address: 2800 Plymouth Rd, NCRC 100-1004
Ann Arbor, MI 48109-2800 
Ph. (734) 764-8848 Fax. (734) 615-0507

Research reported in this publication was supported by the National Cancer Institutes of
Health under Award Number P30CA046592. The content is solely the responsibility
of the authors and does not necessarily represent the official views of the
National Institutes of Health.

Research reported in this publication was supported by the National Cancer Institutes of
Health under Award Number P30CA046592 by the use of the following Cancer Center
Shared Resource(s): Biostatistics, Analytics & Bioinformatics; Flow Cytometry;
Transgenic Animal Models; Tissue and Molecular Pathology; Structure & Drug
Screening; Cell & Tissue Imaging; Experimental Irradiation; Preclinical
Imaging & Computational Analysis; Health Communications; Immune Monitoring;
Pharmacokinetics)

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